Syed Mohammed Karim, MD| Orthopedic Surgery, Orthopedic Oncology | MedStar Health
Syed Mohammed Karim

Syed Mohammed Karim, MD
Provider is directly employed by MedStar Health

4.9 out of 5 (68 reviews)

Specialties: Orthopedic Surgery, Orthopedic Oncology

Languages: Urdu, Hindi, English

About me

S. Mohammed Karim, MD is a board-certified orthopaedic surgeon who is dual fellowship trained in spine surgery and orthopaedic oncology—one of only a handful of surgeons nationwide with such training and experience. At MedStar Health, he specializes in the surgical treatment of patients with bone and soft tissue tumors / cancers. He sees patients at MedStar Franklin Square Medical Center and MedStar Union Memorial Hospital.

As a comprehensive musculoskeletal and spinal oncology surgeon, Dr. Karim enjoys helping those with both primary tumors (such as sarcomas) and metastatic tumors throughout the entire body including the spine, sacrum, pelvis, and extremities. He performs surgery for tumors causing spinal cord compression; spinal fractures/instability from tumors; pathologic or impending fractures in the arms, legs, and pelvis; and malignant bone and soft tissue tumors in all parts of the body. Dr. Karim believes firmly that cancer care is a “team sport” and works closely with medical oncologists, radiation oncologists, pathologists, radiologists, plastic surgeons, and other surgical subspecialists of MedStar Health to provide the best treatment possible to each patient. In addition to cancer patients, he surgically treats those with degenerative spine conditions (such as spinal stenosis, spondylolisthesis, cervical myelopathy, and bulging discs), spinal trauma, spinal cord injuries, and spinal infections.

In addition to caring for patients, Dr. Karim conducts clinical research to improve the outcomes of patients with musculoskeletal and spinal tumors. His research has been published in peer-reviewed journals and presented at international conferences. Dr. Karim is a member of the AOSpine Knowledge Forum Tumor – an international group of surgeons and other cancer specialists who perform research to improve the care of patients with spinal tumors. He is also a member of the American Academy of Orthopaedic Surgeons and the North American Spine Society, for which he holds Committee Appointments in Spine Oncology, Robotics and Enabling Technology, and Resident and Fellow Education. He has a keen interest in education and enjoys teaching and mentoring medical students, residents, and fellows both in and out of the operating room. Beyond his medical career, Dr. Karim is a proud member of the Civil Air Patrol.

Clinical areas of focus

  • Angiosarcoma
  • Benign Bone Tumor
  • Bone Biopsy
  • Bone Cancer Surgery
  • Bone Cyst
  • Bone Metastasis
  • Bone Metastasis Treatment
  • Bone Sarcoma Surgery
  • Flap Surgery
  • Ganglion Cyst Excision
  • Mesothelioma
  • Multiple Myeloma
  • Resection Of Soft Tissue Tumor
  • Salvage Surgery
  • Spinal Spondylolysis Treatment
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Conditions and procedures

Conditions I treat

  • Angiosarcoma
  • Benign Bone Tumor
  • Bladder Carcinoma
  • Bone Cancer
  • Bone Cyst
  • Bone Density Disorder
  • Bone Discontinuity
  • Bone Lesions
  • Bone Metastasis
  • Bone Sarcoma
  • Bone Tumor
  • Brown Tumor
  • Femur Shaft Fracture
  • Fibrosarcoma
  • Liposarcoma
  • Malignant Neoplasm Of Connective And Soft Tissue
  • Mesothelioma
  • Metastatic Bone Disease
  • Multiple Myeloma
  • Neoplasm Of Uncertain Behavior
  • Nerve Tumors
  • Pathological Fracture
  • Pelvic Tumor
  • Skull Base Tumor
  • Soft Tissue Sarcoma
  • Thigh Fracture
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Procedures I perform

  • Amputation Revision
  • Bone Biopsy
  • Bone Cancer Surgery
  • Bone Graft
  • Bone Metastasis Treatment
  • Bone Sarcoma Surgery
  • Ewing's Sarcoma Treatment
  • Femur Excision
  • Femur Fracture Stabilization
  • Flap Surgery
  • Forequarter Amputation
  • Ganglion Cyst Excision
  • Heel Tendon Repair
  • Hindquarter Amputation
  • Hip Distraction
  • Hip Replacement For Metastatic Bone Disease
  • Knee Amputation
  • Metastatic Bone Disease Treatment
  • Pelvic Tumor Resection
  • Proximal Humerus Replacement
  • Reconstruction For Bone Defects
  • Resection Of Soft Tissue Tumor
  • Salvage Surgery
  • Soft Tissue Sarcoma Surgery
  • Spinal Spondylolysis Treatment
  • Toe Amputation
  • Vertebroplasty For Vertebral Compression Fractures
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Practice locations

Distance from Change LocationEnter your Location

3333 N Calvert St
Ste 655
Baltimore, MD, 21218

410-554-2715

Fax 443-656-9320

Get Directions

miles away

Fax 443-656-9320

9101 Franklin Square Dr
Ste 200
Baltimore, MD, 21237

410-554-2715

Fax 443-656-9320

Get Directions

miles away

Fax 443-656-9320

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

  • List of insurance plans we accept
    • IH-PPO
    • Cigna True Choice Plus Medicare (PPO)
    • CIGNA EPO
    • Blue Choice Advantage
    • BCBS of Michigan (BCN Advantage,Security Blue, Freedom, Medicare PLUS Blue Group PPO)
    • Kaiser Permanente Medicare Advantage Signature and Select
    • Mamsi Life & Health (Indem./PPO) Cardiac Global
    • CareFirst Blue Preferred PPO
    • Healthy Blue (HMO, POS)
    • Aetna Classic 5000
    • Humana Gold Plus HMO
    • Cigna Achieve Medicare (HMO C-SNP)
    • First Health PPO
    • Alterwood Advanatge HMO & DSNP Plans
    • Aetna Elect Choice/ EPO (Aetna Health Fund)
    • Aetna Advantage 6350PD
    • Maryland Physicians Care MCO
    • UnitedHealthcare and AARP Medicare Complete Plans
    • Private Fee-for-Service Plans (PFFS)
    • United Healthcare Select HMO - EPO/NPP
    • Advantra Platinum (PPO)
    • IH-POS
    • UHC Group Medicare Advantage Plans (HMO, POS, PPO)
    • Jai Medical Systems - Maryland Health Choice
    • IH-Open POS Plus
    • Choice POS
    • Anthem BCBS of VA Key Care POS/PPO/Indemnity
    • CareFirst Federal Employee Program (Std. & Basic PPO)
    • Aetna Student Health Insurance
    • Optima Family Care MCO - VA Medicaid MCO
    • United HealthCare Community Plan - Maryland Health Choice Program
    • Lasso Healthcare - Medicare Medical Savings Account
    • CareFirst MedStar Select PPO
    • Aetna Quality Point of Service (POS)
    • CareFirst MedStar PPO
    • Anthem BCBS of VA HealthKeepers Plus
    • IH-Open Network Only Plus
    • IH-HMO
    • Aetna Elect Choice/ Open Access (POS)
    • TriWest Healthcare Alliance
    • Kaiser Permanente Flexible Choice POS Cardiac Global
    • TRICARE East Prime
    • CareFirst Blue Choice Opt Out Open Access
    • Aetna HMO
    • Mamsi Life & Health (Indem./PPO)
    • CareFirst EPO
    • IH-Open POS II
    • United Healthcare Community Plan - VA Medicaid MCO
    • TRICARE for Life East
    • Magellan Complete Care of VA - VA Medicaid MCO
    • Johns Hopkins Advantage MD PLUS PPO
    • CareFirst BlueChoice HMO
    • Aetna Classic 3500
    • Optimum Choice
    • Erickson Advantage Plans
    • Core Essential (HMO)
    • CareFirst Community Health Plan of MD
    • IH-Open EPO Plus
    • MedStar Family Choice - Maryland Health Choice
    • Sentara Health
    • CIGNA HMO & Network (HMO)
    • M.D. IPA (HMO)
    • CIGNA PPO Plus
    • Aetna Medicare Advantage PFFS Plan
    • United Healthcare Select HMO-EPO/NPP Cardiac Global
    • Johns Hopkins Advantage MD HMO
    • Kaiser Permaenete Signature - Added Choice Cardiac Global
    • Johns Hopkins Advantage MD PPO
    • United Healthcare Navigate Cardiac Global
    • MD IPA (HMO) & MD IPA Preferred Cardiac Global
    • Kaiser Maryland Medicaid MCO
    • OA Plus
    • IH-EPO Plus
    • MedStar Family Choice DC Healthcare Alliance
    • CareFirst Maryland Point of Service Plan
    • Medicare Direct
    • Humana Medicare Advantage - PPO
    • MultiPlan, Inc
    • Cigna True Choice Medicare (PPO)
    • IH-POS Plus
    • Veterans Affairs Community Care Network
    • Police and Fire Clinic
    • Choice Fund PPO
    • Choice Care Network/HUMANA (PPO)
    • CIGNA Connect EPO
    • Anthem BCBS Medi Blue SNP
    • CareFirst Blue Choice Opt Out Plus Open Access (POS)
    • Tricare Reserve Select
    • HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
    • Anthem BCBS Medi Blue Plus
    • Choice POS II Open Access
    • UHC Passport
    • CareFirst BlueCross BlueShield Advantage Core/Enhanced
    • Anthem BCBS of VA HealthKeepers (HMO)
    • DC/MD SHOP QHP Small Business Plans
    • Medicare FFS
    • Aetna Better Health of MD
    • Network OA
    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)
    • CareFirst Maryland Indemnity or PPO
    • WellPoint Maryland - Maryland Health Choice
    • Kaiser Permanente HMO Plus and DHMO Plus Member
    • Beech Street PPO
    • BCBS Out-of-State Medicare Plans (Blue Advantage)
    • CIGNA POS/Network POS
    • Options PPO Cardiac Global
    • CIGNA Indemnity
    • Aetna Signature Administrator PPO/TPA
    • Aetna Advantage 6350
    • Kaiser Permanente Select - Added Choice
    • Kaiser Permanente Signature - Added Choice
    • Aetna Better Health of VA
    • United Medicare Private Fee-for-Service (PFFS) plans
    • HumanaChoice Honor's plan PPO
    • Anthem Federal Employee Program Basic
    • Aetna VA Exchange
    • Geisinger Medicare Advantage
    • POS OA
    • UnitedHealthcare Medicare Adv. Special Needs Plans
    • Coventry Health Care National Network PPO
    • Aetna Advantage 5750
    • Aetna Open Choice (PPO)
    • Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
    • United Healthcare Select Plus (POS)
    • CareFirst (NCA) Indemnity
    • Aetna Premier 200PD
    • UnitedHealthcare Individual Exchange Plans
    • Aetna Basic
    • United Healthcare Options (PPO)
    • Employee Health Plan
    • Aetna Traditional Choice (PPO)
    • Anthem Federal Employee Program Standard
    • Cigna Alliance Medicare (HMO)
    • Uniformed Services Family Health Plan
    • AMERIVANTAGE/Amerigroup Community Care
    • Aetna Medicare Advantage HMO & PPO Plans
    • BlueChoice Open Access
    • United Healthcare Choice Plus Cardiac Global
    • HighMark
    • Anthem BCBS of VA HealthKeepers (POS & POS OA)
    • IH-Indemnity
    • IH-Open HMO
    • Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
    • United Healthcare Choice Plus
    • Kaiser Permanente Select
    • Anthem BCBS Medi Blue Dual Adv
    • CareFirst FEP Blue Focus
    • OCI Direct (HMO)
    • Navigate
    • CareFirst Dual Prime HMO-SNP
    • UnitedHealthcare Medicare Advantage DSNP District of Columbia
    • Kaiser Permanente Signature
    • HealthyBlue PPO
    • Medicare Advantage - Advantra Value (PPO)
    • Aetna Worker's Compensation Network
    • NYC Medicare Advantage Plus
    • Coventry of Delaware HMO/PPO
    • AmeriHealth Caritas DC Healthy Families
    • IH-Open HMO Option
    • United Healthcare Choice
    • Optimum Choice Preferred (POS)
    • AmeriHealth Caritas DC Healthcare Alliance
    • Private Health Care Systems (PPO)
    • Cigna Preferred Medicare (HMO)
    • Choice POS II
    • MedStar Family Choice DC Healthy Families
    • Kaiser Permanente Select Cardiac Global
    • TRICARE East Select
    • CareFirst Administrators
    • Kaiser Permanente Medicare Plus
    • Health Services for Children with Special Needs
    • CIGNA PPO
    • CareFirst NASCO
    • Amerigroup DC Healthy Families
    • First Health PPO
    • Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
    • Aetna Managed Choice Open Access (POS)
    • Priority Partners - Maryland Health Choice
    • United Student Resources
    • IH-Network Only Plus
    • Aetna Classic 5000PD
    • CIGNA SureFit (HMO)
    • HumanaChoice PPO
    • Humana Medicare Advantage - HMO Open Access
    • CareFirst Blue Card Program
    • M.D. IPA Preferred (POS)
    • CareFirst Group Medicare Advantage
    • Select HMO/HealthFund/Health Network
    • Cigna TotalCare (HMO D-SNP)
    • Kaiser Permanente Flexible Choice 3-tier POS
    • Amerigroup DC Alliance
    • Great-West Healthcare POS/CIGNA
    • CIGNA HMO Open Access
    • Aetna Managed Choice (POS)
    • Coventry Health Care of Virginia
    • United Healthcare Choice Cardiac Global

Videos

Education

Board Certification: American Board of Orthopaedic Surgery, Orthopaedic Surgery

Fellowship: Mayo Clinic College of Medicine & Science (2021)

Fellowship: University of British Columbia GME (2020)

Residency: Massachusetts General Hospital (2019)

Medical School: Harvard Medical School (2014)

Awards

  • Baltimore Magazine, Top Doc, 2025

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.9
  • Extent to which the care provider listened to you

    4.9
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.9
  • Provider included you in decisions

    4.9
  • Concern the care provider showed for your questions or worries

    4.9
  • Likelihood of recommending this care provider to others

    5
  • Nov 15, 2025

    Great experience

  • Nov 13, 2025

    Very professional

  • Oct 25, 2025

    Dr. Karim is by far the best surgeon. Always takes time to answer questions! Great bedside manner and always has the best interest of his patient in mind! Would highly recommend him to anyone!