Syed Mohammed Karim, MD| Orthopedic Surgery, Orthopedic Oncology | MedStar Health
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Syed Mohammed Karim

Syed Mohammed Karim, MD
Provider is directly employed by MedStar Health

4.9 out of 5 (129 reviews)

Specialties: Orthopedic Surgery, Orthopedic Oncology

Languages: English, Urdu, Hindi

About me

S. Mohammed Karim, MD is a board-certified orthopaedic surgeon who is dual fellowship trained in spine surgery and orthopaedic oncology—one of only a handful of surgeons nationwide with such training and experience. At MedStar Health, he specializes in the surgical treatment of patients with bone and soft tissue tumors / cancers. He sees patients at MedStar Franklin Square Medical Center and MedStar Union Memorial Hospital.

As a comprehensive musculoskeletal and spinal oncology surgeon, Dr. Karim enjoys helping those with both primary tumors (such as sarcomas) and metastatic tumors throughout the entire body including the spine, sacrum, pelvis, and extremities. He performs surgery for tumors causing spinal cord compression; spinal fractures/instability from tumors; pathologic or impending fractures in the arms, legs, and pelvis; and malignant bone and soft tissue tumors in all parts of the body. Dr. Karim believes firmly that cancer care is a “team sport” and works closely with medical oncologists, radiation oncologists, pathologists, radiologists, plastic surgeons, and other surgical subspecialists of MedStar Health to provide the best treatment possible to each patient. In addition to cancer patients, he surgically treats those with degenerative spine conditions (such as spinal stenosis, spondylolisthesis, cervical myelopathy, and bulging discs), spinal trauma, spinal cord injuries, and spinal infections.

In addition to caring for patients, Dr. Karim conducts clinical research to improve the outcomes of patients with musculoskeletal and spinal tumors. His research has been published in peer-reviewed journals and presented at international conferences. Dr. Karim is a member of the AOSpine Knowledge Forum Tumor – an international group of surgeons and other cancer specialists who perform research to improve the care of patients with spinal tumors. He is also a member of the American Academy of Orthopaedic Surgeons and the North American Spine Society, for which he holds Committee Appointments in Spine Oncology, Robotics and Enabling Technology, and Resident and Fellow Education. He has a keen interest in education and enjoys teaching and mentoring medical students, residents, and fellows both in and out of the operating room. Beyond his medical career, Dr. Karim is a proud member of the Civil Air Patrol.

Clinical areas of focus

  • Bone Biopsy
  • Bone Cancer Surgery
  • Bone Cyst
  • Bone Metastasis
  • Bone Metastasis Treatment
  • Bone Sarcoma Surgery
  • Flap Surgery
  • Ganglion Cyst Excision
  • Mesothelioma
  • Multiple Myeloma
  • Resection Of Soft Tissue Tumor
  • Salvage Surgery
  • Spinal Spondylolysis Treatment
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Conditions and procedures

Conditions I treat

  • Angiosarcoma
  • Bladder Carcinoma
  • Bone Cancer
  • Bone Cyst
  • Bone Density Disorder
  • Bone Discontinuity
  • Bone Lesions
  • Bone Metastasis
  • Bone Sarcoma
  • Bone Tumor
  • Brown Tumor
  • Cervical Spine Tumor
  • Chordoma
  • Femur Shaft Fracture
  • Fibrosarcoma
  • Hand Tremor
  • Lipoma
  • Liposarcoma
  • Lumbar Spine Tumor
  • Malignant Neoplasm Of Connective And Soft Tissue
  • Mesothelioma
  • Metastatic Bone Disease
  • Multiple Myeloma
  • Neoplasm Of Uncertain Behavior
  • Nerve Tumors
  • Pathological Fracture
  • Pelvic Tumor
  • Sarcomas Of Skin And Soft Tissue
  • Skull Base Tumor
  • Soft Tissue Sarcoma
  • Spinal Metastases
  • Spine Tumor
  • Thigh Fracture
  • Thoracic Spine Tumor
  • Wrist And Hand Tumors
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Procedures I perform

  • Amputation Revision
  • Bone Biopsy
  • Bone Cancer Surgery
  • Bone Graft
  • Bone Metastasis Treatment
  • Bone Sarcoma Surgery
  • Ewing's Sarcoma Treatment
  • Femur Excision
  • Femur Fracture Stabilization
  • Flap Surgery
  • Forequarter Amputation
  • Ganglion Cyst Excision
  • Heel Tendon Repair
  • Hindquarter Amputation
  • Hip Distraction
  • Hip Replacement For Metastatic Bone Disease
  • Knee Amputation
  • Metastatic Bone Disease Treatment
  • Pelvic Tumor Resection
  • Proximal Humerus Replacement
  • Reconstruction For Bone Defects
  • Resection Of Soft Tissue Tumor
  • Salvage Surgery
  • Soft Tissue Sarcoma Surgery
  • Spinal Spondylolysis Treatment
  • Toe Amputation
  • Vertebroplasty For Vertebral Compression Fractures
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Practice locations

Distance from Change Location Enter your Location

3333 N Calvert St
Ste 655
Baltimore, MD, 21218

410-554-2715
Get Directions

miles away

Fax 443-656-9320

9101 Franklin Square Dr
Ste 200
Baltimore, MD, 21237

410-554-2715
Get Directions

miles away

Fax 443-656-9320

2118 Greenspring Dr
Ste 110
Timonium, MD, 21093

410-554-2715
Get Directions

miles away

Fax 443-656-9320

Insurance

MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.

  • List of insurance plans we accept
    • Kaiser Permanente Signature
    • CareFirst BlueChoice HMO
    • Kaiser Permanente Medicare Advantage Signature and Select
    • Optima Family Care MCO - VA Medicaid MCO
    • CareFirst Maryland Indemnity or PPO
    • CareFirst Dual Prime HMO-SNP
    • Priority Partners - Maryland Health Choice
    • Sentara Health
    • Aetna Managed Choice Open Access (POS)
    • Anthem BCBS Medi Blue SNP
    • BlueChoice Open Access
    • IH-Open POS Plus
    • Johns Hopkins Advantage MD PLUS PPO
    • United Student Resources
    • Humana Medicare Advantage - PPO
    • United Healthcare Options (PPO)
    • OCI Direct (HMO)
    • Humana Gold Plus HMO
    • Aetna Better Health of VA
    • Anthem BCBS of VA HealthKeepers (POS & POS OA)
    • CareFirst Group Medicare Advantage prescription drug benefit (PPO)
    • Anthem BCBS of VA HealthKeepers Plus
    • CareFirst Administrators
    • Coventry Health Care National Network PPO
    • United Healthcare Choice Cardiac Global
    • Choice Care Network/HUMANA (PPO)
    • AMERIVANTAGE/Amerigroup Community Care
    • CareFirst BlueCross BlueShield Advantage Core/Enhanced
    • United Medicare Private Fee-for-Service (PFFS) plans
    • CIGNA POS/Network POS
    • Cigna True Choice Plus Medicare (PPO)
    • Kaiser Maryland Medicaid MCO
    • Geisinger Medicare Advantage
    • United Healthcare Navigate Cardiac Global
    • Select HMO/HealthFund/Health Network
    • CareFirst NASCO
    • Optimum Choice
    • Mamsi Life & Health (Indem./PPO) Cardiac Global
    • DC/MD SHOP QHP Small Business Plans
    • Coventry of Delaware HMO/PPO
    • Lasso Healthcare - Medicare Medical Savings Account
    • Aetna Advantage 5750
    • Aetna Premier 200PD
    • Amerigroup DC Alliance
    • CIGNA PPO Plus
    • Cigna TotalCare (HMO D-SNP)
    • Aetna Classic 3500
    • UHC Group Medicare Advantage Plans (HMO, POS, PPO)
    • OA Plus
    • Kaiser Permanente Medicare Plus
    • Aetna Traditional Choice (PPO)
    • CareFirst Maryland Point of Service Plan
    • Johns Hopkins Advantage MD PPO
    • Aetna Elect Choice/ EPO (Aetna Health Fund)
    • Medicare FFS
    • MultiPlan, Inc
    • Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
    • HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
    • United Healthcare Select HMO-EPO/NPP Cardiac Global
    • Aetna Managed Choice (POS)
    • POS OA
    • AmeriHealth Caritas DC Healthcare Alliance
    • Advantra Platinum (PPO)
    • IH-Indemnity
    • TRICARE East Prime
    • Tricare Reserve Select
    • TRICARE East Select
    • TRICARE for Life East
    • Choice POS II
    • Cigna Achieve Medicare (HMO C-SNP)
    • Private Health Care Systems (PPO)
    • IH-Network Only Plus
    • CareFirst EPO
    • Beech Street PPO
    • Aetna Student Health Insurance
    • CareFirst Blue Choice Opt Out Plus Open Access (POS)
    • CIGNA HMO & Network (HMO)
    • CIGNA Indemnity
    • First Health PPO
    • HighMark
    • Aetna Classic 5000
    • United Healthcare Community Plan - VA Medicaid MCO
    • CIGNA SureFit (HMO)
    • Medicare Advantage - Advantra Value (PPO)
    • Choice Fund PPO
    • Police and Fire Clinic
    • Navigate
    • Cigna Preferred Medicare (HMO)
    • Health Services for Children with Special Needs
    • Choice POS
    • Aetna VA Exchange
    • Kaiser Permanente Flexible Choice POS Cardiac Global
    • MedStar Family Choice DC Healthcare Alliance
    • United Healthcare Select Plus (POS)
    • Amerigroup DC Healthy Families
    • CareFirst MedStar Select PPO
    • Core Essential (HMO)
    • Veterans Affairs Community Care Network
    • Aetna Better Health of MD
    • Coventry Health Care of Virginia
    • M.D. IPA Preferred (POS)
    • United Healthcare Choice Plus
    • Aetna Medicare Advantage HMO & PPO Plans
    • CIGNA EPO
    • WellPoint Maryland - Maryland Health Choice
    • CareFirst Blue Card Program
    • Kaiser Permanente HMO Plus and DHMO Plus Member
    • CIGNA Connect EPO
    • Anthem Federal Employee Program Basic
    • Options PPO Cardiac Global
    • Aetna Quality Point of Service (POS)
    • MD IPA (HMO) & MD IPA Preferred Cardiac Global
    • Aetna Classic 5000PD
    • IH-EPO Plus
    • CareFirst MedStar PPO
    • CareFirst Group Medicare Advantage
    • Kaiser Permanente Select Cardiac Global
    • United Healthcare Select HMO - EPO/NPP
    • IH-POS Plus
    • CareFirst Blue Choice Opt Out Open Access
    • UnitedHealthcare Individual Exchange Plans
    • Choice POS II Open Access
    • Great-West Healthcare POS/CIGNA
    • BCBS of Michigan (BCN Advantage,Security Blue, Freedom, Medicare PLUS Blue Group PPO)
    • NYC Medicare Advantage Plus
    • Healthy Blue (HMO, POS)
    • Erickson Advantage Plans
    • Alterwood Advanatge HMO & DSNP Plans
    • Aetna Medicare Advantage PFFS Plan
    • Employee Health Plan
    • Aetna Basic
    • CareFirst Blue Preferred PPO
    • CareFirst Community Health Plan of MD
    • Optimum Choice Preferred (POS)
    • Anthem BCBS of VA Key Care POS/PPO/Indemnity
    • Network OA
    • Cigna Alliance Medicare (HMO)
    • Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
    • UnitedHealthcare Medicare Adv. Special Needs Plans
    • United HealthCare Community Plan - Maryland Health Choice Program
    • Aetna Worker's Compensation Network
    • CIGNA PPO
    • Magellan Complete Care of VA - VA Medicaid MCO
    • Cigna True Choice Medicare (PPO)
    • Jai Medical Systems - Maryland Health Choice
    • UHC Passport
    • Aetna Advantage 6350
    • HealthyBlue PPO
    • Anthem BCBS Medi Blue Plus
    • Aetna Elect Choice/ Open Access (POS)
    • Humana Medicare Advantage - HMO Open Access
    • United Healthcare Choice Plus Cardiac Global
    • Blue Choice Advantage
    • UnitedHealthcare Medicare Advantage DSNP District of Columbia
    • UnitedHealthcare and AARP Medicare Complete Plans
    • Kaiser Permaenete Signature - Added Choice Cardiac Global
    • Anthem BCBS of VA HealthKeepers (HMO)
    • CareFirst Federal Employee Program (Std. & Basic PPO)
    • CareFirst (NCA) Indemnity
    • HumanaChoice Honor's plan PPO
    • Kaiser Permanente Signature - Added Choice
    • CIGNA HMO Open Access
    • BCBS Out-of-State Medicare Plans (Blue Advantage)
    • IH-Open HMO
    • HumanaChoice PPO
    • Kaiser Permanente Select - Added Choice
    • Aetna Open Choice (PPO)
    • Anthem Federal Employee Program Standard
    • United Healthcare Choice
    • Mamsi Life & Health (Indem./PPO)
    • IH-Open EPO Plus
    • Aetna Advantage 6350PD
    • IH-Open Network Only Plus
    • Aetna Signature Administrator PPO/TPA
    • First Health PPO
    • Kaiser Permanente Flexible Choice 3-tier POS
    • MedStar Family Choice - Maryland Health Choice
    • M.D. IPA (HMO)
    • IH-HMO
    • Anthem BCBS Medi Blue Dual Adv
    • Private Fee-for-Service Plans (PFFS)
    • Aetna HMO-Open Access/Select OA/HealthFund/Health Network Option OA
    • IH-PPO
    • TriWest Healthcare Alliance
    • CareFirst FEP Blue Focus
    • Medicare Direct
    • IH-POS
    • IH-Open POS II
    • Kaiser Permanente Select
    • MedStar Family Choice DC Healthy Families
    • Aetna HMO
    • Johns Hopkins Advantage MD HMO
    • IH-Open HMO Option
    • Uniformed Services Family Health Plan
    • AmeriHealth Caritas DC Healthy Families
    • Maryland Physicians Care MCO

Videos

Education

Board Certification: American Board of Orthopedic Surgery, Orthopedic Surgery

Fellowship: Mayo Clinic College of Medicine & Science (2021)

Fellowship: University of British Columbia GME (2020)

Residency: Massachusetts General Hospital (2019)

Medical School: Harvard Medical School (2014)

Awards

  • Baltimore Magazine, Top Doc, 2025

Ratings and reviews

  • Explanations the care provider gave you about your problem or condition

    4.9
  • Extent to which the care provider listened to you

    4.8
  • Care provider’s discussion of any proposed treatment (options, risks, benefits, etc.)

    4.9
  • Provider included you in decisions

    4.9
  • Concern the care provider showed for your questions or worries

    4.9
  • Likelihood of recommending this care provider to others

    4.9
  • May 19, 2026

    Good experience

  • May 17, 2026

    Dr. Karim is one of the best doctors I have seen lately. He listened to my concerns and understood them

  • Apr 30, 2026

    Dr Karim was all that you wanted - outstanding knowledge and bedside manner