Gholam K Motamedi, MD| Neurology | MedStar Health
About me
Gholam K. Motamedi, MD, is a professor and director of the Comprehensive Epilepsy Center in the Department of Neurology at MedStar Georgetown University Hospital. Dr. Motamedi chose his specialty because he feels that neuroscience is at the frontier of science. His philosophy of care involves undertaking a comprehensive work-up, making the correct diagnosis and administering the most efficient treatment possible for the patient.
Dr. Motamedi has published numerous original research studies, reviews and has contributed several book chapters to works in the fields of epilepsy and sleep disorders. Some of his research studies include investigating potentially therapeutic effects of direct brain stimulation in patients with epilepsy, potentially therapeutic effects of direct brain stimulation and brain cooling (hypothermia) in animal models of epilepsy, basic cellular and molecular mechanisms underlying the development of epilepsy, particular genetic forms of epilepsy mimicking sleep disorders, sleep apnea, monitoring cardiac telemetry and pulse oximetry in patients with epilepsy undergoing continuous video-EEG monitoring and retrospective study of in utero antiepileptic drug effects on neurodevelopment. Dr. Motamedi has also received several awards for excellence in patient treatment, teaching and research.
Professional Association Memberships
- American Epilepsy Society
- American Academy of Sleep Medicine
- American Neurological Association
Clinical areas of focus
- Atonic Epilepsy Treatment
- Central Sleep Apnea
- Central Sleep Apnea Treatment
- Convulsions
- Electroencephalogram Review
- Epilepsy Surgery
- Inpatient Epilepsy Monitoring
- Seizure Treatment
- Tonic Clonic Seizure Management
- Vagus Nerve Stimulation
Conditions and procedures
Conditions I treat
- Abnormal Body Structure Imaging
- Abnormal Function Study Results
- Abnormal Movements
- Abnormal Mri
- Abscess Of The Brain
- Adult Attention Deficit Hyperactivity Disorder (ADHD)
- Anxiety
- Autism Spectrum Disorder
- Back Pain
- Bipolar Disorder
- Bleeding In Brain
- Brain Aneurysm
- Brain Disorders
- Central Sleep Apnea
- Cerebral Edema
- Cerebral Palsy
- Cerebrovascular Diseases
- Cocaine Related Disorders
- Cognitive Function Disorders
- Conductive Hearing Loss
- Convulsions
- Degenerative Diseases Of Nervous System
- Dementia
- Demyelinating Diseases Of Central Nervous System
- Disorders Of Autonomic Nervous System
- Disorders Of Trigeminal Nerve
- Disturbances Of Cerebral Status Of Newborn
- Disturbances Of Skin Sensation
- Dorsalgia
- Dyslexia And Symbolic Dysfunctions
- Dystonia
- Emotional Disorders
- Encephalitis, Myelitis And Encephalomyelitis
- Epilepsy
- Epilepsy And Seizures
- Extrapyramidal And Movement Disorders
- Facial Nerve Disorder
- Family History Of Malignant Neoplasm
- Gait And Balance Problems
- General Sensations And Perceptions
- Head Injury
- Headache
- Hemangioma
- Hemiplegia
- Herpes
- Hydrocephalus
- Idiopathic Neuropathy
- Inflammatory Polyneuropathy
- Intracerebral Hemorrhage
- Ischemic Stroke
- Lack Of Coordination
- Maternal Diseases
- Meningitis
- Menioma Brain Tumor
- Migraine
- Multiple Sclerosis
- Muscle Disorders
- Myoneural Disorders
- Myopathies
- Nervous And Musculoskeletal Symptoms
- Neurodegeneration
- Neurofibromatosis
- Nontraumatic Subarachnoid Hemorrhage
- Ocular Myasthenia Gravis
- Paralytic Strabismus
- Paralytic Syndrome
- Parkinson's Disease
- Personal History Of Diseases And Conditions
- Pervasive Developmental Disorder
- Poisoning
- Postprocedural States
- Precerebral Artery Occlusion
- Sarcoidosis
- Secondary Malignant Neoplasm Of Brain
- Sensory Neuropathy
- Sleep Disorders
- Somnolence, Stupor And Coma
- Speech Disturbances
- Spinal Cord Injury
- Sports Concussion
- Subarachnoid Hemorrhage In Newborn
- Subcortical Infarction
- Tic Disorder
- Transient Cerebral Ischemic Attacks
- Traumatic Brain Injury
- Type 2 Diabetes Mellitus
- Vagus Nerve Stimulation
- Vascular Dementia
- Vascular Malformations Of The Brain
- Vasculitis
- Vestibular Disorders
- Vision Disturbances
- Vitamin Deficiency
Procedures I perform
- Brain Wave Testing
- Central Nervous Electrical Activity Monitoring
- Central Sleep Apnea Treatment
- Chronic Headache Treatment
- Computerized Tomography (CT) Scan
- Electroencephalogram Review
- Electroencephalogram Setup And Takedown
- Electronic Analysis Of Implanted Neurostimulator
- Epilepsy Surgery
- Functional Mri
- Geriatric Sleep Disorder Treatment
- Inpatient Epilepsy Monitoring
- Magnetic Resonance Imaging (MRI)
- Measurement Of Central Nervous Electrical Activity
- Median Nerve Conduction Studies
- Multiple Sclerosis (MS) Treatment
- Neurodegenerative Disease Treatment
- Neuromuscular Monitoring
- Neuromuscular Reeducation For Muscle Control
- Percutaneous Tibial Nerve Stimulation
- Polysomnography
- Seizure Treatment
- Sleep Study
- Soft Tissue Neck Ct Without Contrast
- Somatosensory Evoked Potentials
- Stroke Management
- Vagus Nerve Stimulation
Practice locations
Distance from Change LocationEnter your Location
3800 Reservoir Rd NW Pasquerilla Healthcare Center Washington, DC, 20007
301-774-8956Fax 410-354-4565
Insurance
MedStar Health accepts most major health insurance plans. If you are uncertain as to whether your individual health insurance plan is accepted at MedStar Health, please call your insurance company.
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List of insurance plans we accept
- Optima Family Care MCO - VA Medicaid MCO
- Kaiser Maryland Medicaid MCO
- CareFirst Group Medicare Advantage
- TRICARE East Prime
- CIGNA Connect EPO
- Medicare FFS
- Cigna Achieve Medicare (HMO C-SNP)
- UnitedHealthcare and AARP Medicare Complete Plans
- CareFirst FEP Blue Focus
- Humana Gold Plus HMO
- Private Health Care Systems (PPO)
- Aetna Premier 200PD
- CIGNA SureFit (HMO)
- UHC Group Medicare Advantage Plans (HMO, POS, PPO)
- Aetna Elect Choice/ EPO (Aetna Health Fund)
- Jai Medical Systems - Maryland Health Choice
- POS OA
- CareFirst NASCO
- United Healthcare Select Plus (POS)
- BCBS Out-of-State Medicare Plans (Blue Advantage)
- MD IPA (HMO) & MD IPA Preferred Cardiac Global
- CIGNA HMO & Network (HMO)
- Navigate
- Core Essential (HMO)
- Aetna HMO
- IH-EPO Plus
- AmeriHealth Caritas DC Healthcare Alliance
- CareFirst Group Medicare Advantage prescription drug benefit (PPO)
- Uniformed Services Family Health Plan
- CareFirst Maryland Point of Service Plan
- IH-Open Network Only Plus
- Cigna Preferred Medicare (HMO)
- UnitedHealthcare Medicare Adv. Special Needs Plans
- CareFirst Federal Employee Program (Std. & Basic PPO)
- Erickson Advantage Plans
- IH-Open EPO Plus
- First Health PPO
- Private Fee-for-Service Plans (PFFS)
- Choice Care Network/HUMANA (PPO)
- Anthem BCBS of VA HealthKeepers (HMO)
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- Great-West Healthcare POS/CIGNA
- Aetna Medicare Advantage PFFS Plan
- Anthem BCBS of VA Key Care POS/PPO/Indemnity
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- United Healthcare Choice Cardiac Global
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- Anthem BCBS Medi Blue SNP
- NYC Medicare Advantage Plus
- Employee Health Plan
- TriWest Healthcare Alliance
- TRICARE for Life East
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- UHC Passport
- Network OA
- WellPoint Maryland - Maryland Health Choice
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- DC/MD SHOP QHP Small Business Plans
- Healthy Blue (HMO, POS)
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- Aetna Traditional Choice (PPO)
- Kaiser Permanente Select Cardiac Global
- Health Services for Children with Special Needs
- Optimum Choice & Optimum Choice Preferred (POS) Cardiac Global
- IH-Open HMO Option
- Aetna Worker's Compensation Network
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- Kaiser Permanente Select - Added Choice
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- Lasso Healthcare - Medicare Medical Savings Account
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- Fee-for-Service (FFS) District of Columbia, Maryland and Virginia Medicaid
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- Aetna Classic 5000
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- United Healthcare Choice Plus Cardiac Global
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- Aetna Advantage 6350
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- CIGNA POS/Network POS
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- Aetna Classic 5000PD
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- Anthem Federal Employee Program Basic
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- Coventry Health Care National Network PPO
- Aetna Basic
- Aetna Quality Point of Service (POS)
- Aetna Classic 3500
- CIGNA PPO Plus
- MedStar Family Choice DC Healthcare Alliance
- M.D. IPA (HMO)
- Aetna Medicare Advantage HMO & PPO Plans
- OA Plus
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- Kaiser Permanente Flexible Choice 3-tier POS
- IH-Network Only Plus
- Select HMO/HealthFund/Health Network
- HUMANA/Choice Care Medicare Plans (Choice, Gold Choice)
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- Johns Hopkins Advantage MD HMO
- United Healthcare Community Plan - VA Medicaid MCO
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Videos
Education
Board Certification: American Board of Psychiatry and Neurology, Psychiatry and Neurology
Board Certification: American Board of Psychiatry and Neurology, Psychiatry and Neurology
Board Certification: American Board of Psychiatry and Neurology, Psychiatry and Neurology
Fellowship: Johns Hopkins University School of Medicine (1999)
Residency: Baylor College of Medicine-Surgical Critical Care Fellowship (1998)
Internship: Yale-New Haven Hospital (1995)
Medical School: Tehran University of Medical Sciences (1990)
Awards
- Excellence in Teaching Medical Students, Georgetown 2006-7
- National Epifellow Foundation (NEF) research award 1999
- American Epilepsy Society meeting Topscholar fellow award Dec. 1998
- American Academy of Neurology Annual Meeting Scholarship Apr. 1998
- World Health Organization (WHO) Scholarship on Epidemiology, Bangalore, India Jan-Mar. 1990
- Best Doctors in greater DC area; Washington Post, 2011-2013
- Fellow of American Neurological Association (FANA), 2012
- Castle Connolly Top Doctors, 2016-2025
- Fellow of the American Epilepsy Society (FAES), 2017
Hospital affiliations
News and publications
Select original papers:
- Tirol FG, Levine MR, Wang T, Cho YW, Motamedi GK. An FP's guide to caring for patients with seizure and epilepsy. J Fam Pract. 2023 Nov;72(9):366-385. doi: 10.12788/jfp.0685.PMID: 37976335.
- Park KM, Kim KT, Lee DA, Motamedi GK, Cho YW. Structural and functional multilayer network analysis in restless legs syndrome patients. J Sleep Res. 2023 Nov 14:e14104. doi: 10.1111/jsr.14104. Online ahead of print.PMID: 37963544.
- Park KM, Kim KT, Lee DA, Motamedi GK, Cho YW. Glymphatic system dysfunction in restless legs syndrome: evidenced by diffusion tensor imaging along the perivascular space. Sleep. 2023 Nov 8;46(11):zsad239. doi: 10.1093/sleep/zsad239.PMID: 37702251.
- Wang T, Raman VK, Motamedi GK.Neurohospitalist. Continuous EEG Characteristics in Critically ill Patients Presenting With Seizures Prior to Death From Cardiac Arrest. 2023 Oct;13(4):371-375. doi: 10.1177/19418744231174950. Epub 2023 May 12.PMID: 37701258
- Motamedi GK, Peter Jeliazkov, Oyegbile T, Song S, Sharma VD, Mihri Mete, Turkeltaub PE, Cho YW, Wu JY. Transcranial alternating current stimulation (tACS) as a treatment for insomnia. Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques, 1-4. doi:10.1017/cjn.2022.33.
- Tacrolimus-induced generalized tremor with excellent response to primidone. Lenka A, King C, Soni M, Hu N, Motamedi GK. Annals of Movement Disorders. 2022. DOI: 10.4103/AOMD.AOMD_30_21.
- Wang T, Safadi AL, Lee ECC, Bicher N, Barry B, Sirdar B, Motamedi GK, Osborne B. Clinical Reasoning: A 56-Year-Old Man With Unusual Presentation of Subacute Encephalopathy and Seizure. Neurology. 2022 Jan 4;98(1):e95-e102. doi: 10.1212/WNL.0000000000012951. Epub 2021 Oct 14
- Song ML, Park KM, Motamedi GK, Cho YW. Cognitive behavioral therapy for insomnia in restless legs syndrome patients. Sleep Med. 2020 Oct;74:227-234. doi: 10.1016/j.sleep.2020.07.011. Epub 2020 Jul 19.
- Stevens JM, Levine MR, Constantino AE, Motamedi GK. Case of fatal familial insomnia caused by a d178n mutation with phenotypic similarity to Hashimoto's encephalopathy. BMJ Case Rep. 2018 Jul 15;2018. DOI: 10.1136/bcr-2018-225155. PMID: 30012679.
- Oyegbile T, Santos C, Zecavati N, Berkowitz F, Lee C, Motamedi G, VanMeter J, Gaillard WD, Hermann B. Executive Dysfunction is Associated with an Altered Executive Control Network in Pediatric Temporal Lobe Epilepsy. Epilepsy & Behavior. 2018 Sep;86:145-152. DOI: 10.1016/j.yebeh.2018.04.022. PMID: 30001910.
- Anyanwu C, Motamedi GK. Diagnosis and Surgical Treatment of Drug-Resistant Epilepsy. Brain Sci. 2018, 8(4), 49 doi:10.3390/brainsci8040049.
- Cho YW, Kang MS, Kim KT, Moon HG, Korostyshevskiy VP, Motamedi GK, Yang KI. Comorbid Insomnia with obstructive sleep apnea: clinical characteristics and risk factors. J Clin Sleep Med. 2018;14(3):409417. DOI:10.5664/jcsm.6988. PMID: 29458695.
- Cho YW, Kang MS, Kim KT, Do SY, Lim JG, Lee SY, Motamedi GK. Quantitative sensory test for primary restless legs syndrome/Willis-Ekbom Disease (RLS/WED) Using the Current Perception Threshold Test. J Clin Sleep Med. 2017 Feb;30:19-23. PMID: 28215248.
- Kim KT, Motamedi GK, Cho YW. Quality of life in patients with an idiopathic rapid eye movement sleeps behavior disorder in Korea. J Sleep Research. 2016 Dec 26. doi: 10.1111/jsr.12486. PMID: 28019055.
- Wickwire EM, Williams SG, Roth T, Capaldi VF, Jaffe M, Moline M, Motamedi GK, Morgan GW, Mysliwiec V, Germain A, Pazdan RM, Ferziger R, Balkin TJ, MacDonald ME, Macek TA, Yochelson MR, Scharf SM, Lettieri CL. Sleep, sleep disorders, and mild traumatic brain injury - What we know and what we need to know: Findings from a national working group. Neurotherapeutics. 2016 Apr;13(2):403-17.
- Vitantonio D, Xu W, Geng X, Takagaki K, Motamedi GK, Wu JY. Emergence of dominant initiation sites for interictal spikes in rat neocortex. J Neurophysiol. 2015 Oct 7.
- Kim KT, Cho, M.D YW, Kim DE, M.D, Hwang SH, Song ML, Motamedi GK. Two Subtypes of Positional Obstructive Sleep Apnea: Supine-predominant and Supine-isolated OSA. Clinical Neurophysiology. 2015 Jun 16.
- Motamedi GK, Wheeler MG. Daily episodes of confusion altered behavior · chronic sleep deprivation · Dx? J Fam Pract. 2015 Feb;64(2):92-6.
- Takagaki K, Morales MK, Vitantonio D, Berkowitz F, Bell WL, Kumar PN, Motamedi GK. Periodic lateralized epileptiform discharges (PLEDs) in patients with neurosyphilis and HIV infection. Clin EEG Neurosci. 2014 Oct 17.
- Takagaki K, Russell J, Lippert MT, Motamedi GK. Interhemispheric delay of alpha phase in autistic children. Clinical Neurophysiology. 2014 May 27.
- Vallabhaneni M, Baltassari L, Scribner JT, Cho YW, Motamedi GK. Wicket Spikes in Patients Undergoing Long-term Video-EEG Monitoring. Seizure, The European Journal of Epilepsy, 22 (2013) 14–19.
- Anyanwu C, Ghavami F, Schuelein M, Motamedi GK. Ethosuximide-induced conversion of typical childhood absence to Rolandic spikes? J Child Neurol. 2013 Jan;28(1), pp. 109–112.
- Raybould JE, Alfers C, Cho YW, Wang H, Nawar S, Epstein SA, Motamedi GK. Is EEG Screening for Temporal Lobe Epilepsy in Patients with Acute Psychosis warranted? J Neuropsychiatry Clin Neurosci. 2012 Sep 1;24(4):452-7.
- Motamedi GK, Gonzalez-sulser A, Dzakpasu R, Vicini S. Cellular mechanisms of desynchronizing effects of hypothermia in an in vitro epilepsy model. Neurotherapeutics 2012 Jan;9(1):199-209.
Select editorials:
- Motamedi GK. Psychogenic nonepileptic seizures: A disconnect between mind and body. Epilepsy & Behavior. 2018 Jan;78:293-294. PMID: 29239801.
- Motamedi GK. Obstructive sleep apnea; is it the anatomy or physiology?. Clinical Neurophysiology, 125 (2014) 1717–1718.
Select reviews:
- Motamedi GK, Lesser RP, Vicini S. Therapeutic brain hypothermia, its mechanisms of action, and its prospects as a treatment for epilepsy. Epilepsia, 54(6):959–970, 2013.
- Anyanwu C, Motamedi GK. Management of pediatric refractory epilepsy. Journal of Pediatric Epilepsy 1 (2012) 203–209.
Select book chapters:
- Motamedi GK, Gotman J, Lesser RP. Technical and practical aspects of invasive recordings and brain stimulation. In: Lhatoo, Sam; Kahane, Philippe; Lüders, Hans, Editors. Invasive Studies of the Human Epileptic Brain: Principles and Practice of Invasive Brain Recordings and Stimulation in Epilepsy. Oxford University Press;1st Edition, 2018. In Press.
- Anyanwu C, Motamedi GK. Diagnosis and surgical treatment of epilepsy. In: Boling, Warren, Editor. Diagnosis and Surgical Treatment of Epilepsy. Brain Sciences; 1st Edition, 2018.
- Motamedi, GK. Epilepsy surgery and neurostimulation. In: Koubeissi MZ, Editor. Epilepsy Board Review: A Comprehensive Guide. DeveD, Inc. In Press.
- Motamedi GK, Lesser RP. Familial and Sporadic Nocturnal Frontal Lobe Epilepsy (NFLE) - Electroclinical Features. In: Osorio I, Zaveri HP, Frei MG, Arthurs S, Editors. Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering and Physics. CRC Press, 2011. p. 445-50.
Online publications:
- Motamedi GK. Short GAA trinucleotide repeat expansion and late onset Friedreich's Ataxia. Case reports, Baylor Neurology Web Site, (http://www.bcm.edu/neurology/challeng/pat25/summary.html) 1998.
- Motamedi GK. Neuro-cysticercosis. Case reports, Baylor Neurology Web Site, (http://www.bcm.edu/neurology/challeng/pat10/summary.html) 1997.
Select abstracts:
- A Case of Fatal Familial Insomnia Caused by a D178N Mutation with Phenotypic Similarity to Hashimoto’s Encephalopathy. Stevens J, Levine M, Amjad F, Constantino A, Tornatore CS, Motamedi GK. MedStar Health Research Symposium. 2017.
- Miller A, Takagaki K, Cho M, Cho YW, Motamedi GK. Characterization of High Frequency Oscillations in a Patient with Epilepsy. Annals of Neurology Vol 80 (suppl 20) 2016.
- Jeon JY, Moon HJ, Motamedi GK, Cho YW. Cefepime induced encephalopathy in a tertiary medical center in Korea. Annual Meeting of the American Epilepsy Society, 2014.
- Vitantonio D, Xu W, Wu J, Motamedi G. Early involvement of the contralateral cortex as a spatial organizer of the interictal spikes. American Epilepsy Society meeting, 2012.
- Gonzalez-Sulser A, Vicini S, Motamedi GK, Avoli M, Dzakpasu R. Pharmacological regulation of interictal activity studied with a perforated multi-electrode array in an in vitro epilepsy model. Society for Neuroscience annual meeting, 2010.
- Cho YW, Yi SD, Kim DH, Shin WC, Motamedi GK. The effect of levetiracetam monotherapy on subjective sleep quality and objective sleep parameters in patients with epilepsy, compared with the effect of carbamazepine-CR monotherapy. European Conference on Epilepsy & Society, 2010.
- Motamedi GK, Gonzalez-Sulser A, David Press D, Dzakpasu R, Vicini S. Effects of cooling on synchronous epileptiform discharges in mice hippocampus and cortex recorded through a multi-electrode array (MEA). Epilepsia, 50(Suppl. 11):1–502, 2009.
- VanMeter JW, Newlin DB, Renton R, Breeden A, Motamedi G, Kuch J. Using MR Spectroscopy to Measure Cortical Changes in a Pharmacological Agent in Real-Time. Organization of Human Brain Mapping. San Francisco, CA, 2009.
- Motamedi GK, Partridge JG, Vicini S. Asynchronous and differential responses of the hippocampal pyramidal cells and interneurons to hypothermia. Epilepsia, 49(suppl. 7):1–498, 2008.
- Slezicki KI, Cho YW, Brock MS, Pfeiffer M, McVearry K, Tractenberg RE, Motamedi GK. Assessment of handedness in patients with epilepsy. Epilepsia, 49(suppl. 7):1–498, 2008.
- McVearry KM, Motamedi G, Meador K. Behavioral lateralization and prenatal exposure to antiepileptic drugs: Evidence for increased non-right hand preference. Neurotoxicology and Teratology, 30(3), 153-262.